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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f8ff35a233cdcf84b4d25d0ba5394e576a29bb1af727f1286dd2879b4fb5bb3' 
  AND token = 'V2CX8e7LCC4nEtOmcgw7xh6Aw32MR3Phu8nZJpGS28I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}