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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d09655e77b32636008477397fccc46a23af46ed5a396497ae39360e417525a7' 
  AND token = 'CGlclqANW9HZt5FDCHnvHa6pATIes2yhOQCsAVz839M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}