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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51fea076b9ae7599dde8704fba5168c1e4e8db39d51f6e1f1b807ba075384bd4' 
  AND token = 'vMQXdeDEZPjQFJxqjF+1uYgIv+MH4FW45aC8WXMvAEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}