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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73a5688d3d5cc2f0e65bb811a7463023def321e81b2c4f8b3bdec174de2648da' 
  AND token = '1Qm5l+8gQEcAZWnTb4DSKJDVhjdkYQITDmWooCv5n2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}