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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a32e1c0e33464e6e1fdb4411dcded8af05f966a6f91c4992f6f19a3f0a603f22' 
  AND token = 'E5B8tMwvcaM6NQ+RijTSQaDX7MwFKfkOCeU1oR78UwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}