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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00289caf440edc8c865269cd526e991fd91a5d722377b3ebdf76bd833138182c' 
  AND token = 'XDtH3m/TIR+9iyTZMEogdrFJAtyMj+j8aW4F9jNrxlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}