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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b334860b95a35d4353c17132a4550ecd479064d5a814e6c8dd8fbae2f3cd956' 
  AND token = '/RTm2aA+P0I8HLHRyGyMdL6YrtLWrdpKF2tbgbpoK8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}