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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '668f179b200da2935a3ea4f049c378127708a005c1392c8fa110ab5fd8b24f59' 
  AND token = 'VvOony/3Z+XaTI8zZr5XeosImPs9NtyHGdtIUHO5QWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}