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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b14c8bc1ee570dbdcfd8431e8437f9b72e7e48e17ba1827e2eb121099069231' 
  AND token = 'vzbHFiNyS/o8yzEP3GBOK+bbdcK2n3SY6BNa0miSVKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}