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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5086e52b05e56a5ca480ee2a1bad953d520df06a1eb812434450dd88df7ec341' 
  AND token = 'NOAcfuC/IB0OzYkx5hJLL+04/VQRIKTOgAAEMgB8Z1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}