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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50025067adfcc24d2b7315133a826ece3b8aece3b64f02e2903fdc8a7bd98277' 
  AND token = 'lA3SKh+0j3L2NnoPGHUfhZ0RtxQvZ7BhXlK9l/a7HiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}