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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '742e6027e1f0edeaa544799465a9bcb210910e86fe5ea4045c28b3a0bc963e31' 
  AND token = 'G2+WCwiYbJSRuWAeKdwfsx32SJfeJX0nFm0JpnArr1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}