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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c108d4218de4142332d1864cd5a47c15f8eb14410575b1ce7a667dc9e28dd0a' 
  AND token = 'FVkjTJpFDxBmeA+Hx2TZrkw2YTeDJNHtPpwbqY+v09w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}