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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46a1187345c6bc9d521c8ccc422125a7651a38d3a86594be294235ef1a11efd0' 
  AND token = 'Apxlu9R56tmR/4XFi8vVZQEdMc1WNeZSHboPi3yImGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}