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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1c7af992f76e4a6337b01085a4660919260ca202c64e839c8920766836b23b9' 
  AND token = '4NLUBOsKXOoUSaEkm1jZNEymYBdUJtqlcqcZGKJref4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}