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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ef5e1456211b84343c9e778c0cb839533f1788ff33ee98a656b08e671325459' 
  AND token = '2uVa64FAqeeyWUHD8q+dpXaXh5mtcn5RlaRDw7vMv6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}