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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac194430b8a741b20e9f411cd6ab1cf81b23bc834781bf1a4f4d02a0e2d84e1f' 
  AND token = 'adNjNJVFNV9Tm28gN1H4CiHkWm+JEI9nIvgpm906Rx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}