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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa17a7164b928a9151bd59c3f41fd10a512050c1c03aabb5896c4407670355a8' 
  AND token = 'HxQs0xaZfI1GHm9sL8/tcqNNIFDyQJ+PPaJjOZw1jF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}