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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd78897abdf511764d561a4a525115e115fa1cd65fcfbe9c75236720e1ea8d330' 
  AND token = 'I66i+7BLJREKG/MXhaqJuafS5vmhAGfgt8DGiEkvH6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}