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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4ae9a8887481661dc0036c12481ff318ac004de30258617832e7b3f4003280c' 
  AND token = 'iDbhp3MZXWpsd+ESfsk7KFu7Z+PIrWv/p3LW76Bw0TU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}