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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '864f501c687002ac119ff27e3e7436d132efac1f3a5a8926e90f5a4c07336c02' 
  AND token = 'VdV+pps8N8go4nSPERj+dg54Z6kVCiOtiIe/vqAvey4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}