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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c0c7e70cb513f39fbeda6a9d385f502540f7b212f6d5000b2cb6ce3ecc59a7e' 
  AND token = 'OMnNVs99uLHz2tIZzfWihwrniHu7ARvV86NzcVfU0hE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}