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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf6cfc1a9381b4f30df5ce2ece9ce0de7de1a76bdec5b9771850159088900902' 
  AND token = 'HOwSQBKbC9r/DUEjDdWxtzFVUcguOdGIjoEt2KXMc98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}