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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19760a9d8f99d3523fa8e266254cdae011a32f16e38da243adf805e1a8012ddb' 
  AND token = 'TmWp6fMMN3DudKCizUsVhy6wrHwfPtFMrnQocPBkmUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}