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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '629cb440d83e39354157f241ba0931eaf66341da32cb7761ba2f4474dbc495d9' 
  AND token = '6kY6YU39e5aF2dZBvGoUe/qRRS3aqASZar+xQXa5+tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}