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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b49e6f7377835f9a65d82927336ca73749baf980affdc15499d5b49c12a8763' 
  AND token = 'TSD2SirqfjewSaxtPhpyr9dI/GlrudlsCXwu8RKZXGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}