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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5774b74798ca0e1222f50582f57f8bb82d67dfb31cddf9a32d0f880a37fe7694' 
  AND token = '+2UVaz5/rvhJZ60Erqk90/RTHDXUazhrZc3AQuZDAto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}