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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e66e621e0722df5cd989aff4cffc5546c2b07be2b92ab872b7fd1d85d4576de' 
  AND token = '27JxBeNiKuEtLwxjSBheTBdf+Tb6k7AeyPLSHbv9CjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}