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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7a29da82b4fb07dd5716d05c314670703205aa81b23ca212e3ff013f285857f' 
  AND token = 'oTE/hUnqE/4m98bi0cKv46SuJK4Cmd+tGiCECEdyaRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}