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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06aeebb2c15e8060ce0982e1c6aa0b3b56896e8d3878139b085bb143fe4b4182' 
  AND token = 'HLoF2+5w33dPHsR4ACRj/gqSVlwQnTTS1iH84Okj6BM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}