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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da74e0d5658e307044b2a8db3a20da6e2be6e7f8cf55d3cbffd980059925f675' 
  AND token = 'xr/tBTyv6+muMH+wR9/XA1IFJ0VTMJmleahRfDi5Q9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}