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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ec7a18ddfd96e33f644a8f5bd471ebfadce0d19b2361575d304a3597cb4bab3' 
  AND token = 'ZvbFefKQybz/tiL7XHoDVsYoa6ArRDbXkATqYFcAG8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}