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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a5d123a2ba7e1260f22b5eeb86d06cd8bcab33bf09b97fa810afa280cd66bf3' 
  AND token = 'e+K5uMK6BJ7SlbVgRY5ABj6JpYisn3Kp7Rpf1Vg5eY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}