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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654075d6dc32faac5189aeca7e593d783a22b1bbc96285c8e8d2a4f95105c1b9' 
  AND token = 'dCtQY2ZBR5BAgC7H3b7oMmONQo+KcGWxQzkwrIgbM3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}