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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14ecf11da8033a99c20b34f96393b0c176fe6a610d5174f11cb28c4d81ae9b46' 
  AND token = 'bwACbJfa1shee++0/SZJ9Z3OVNjIbBuotfBoCMlxUOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}