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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49fd8845d70b6b03cc6689c7083aae442c6bc85a4817f0b740ab56956f4f0384' 
  AND token = 'JYG/eeu9mDxX3p2GaRyYfIY5JnOO/4MS2gcH9/dDwLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}