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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88cddb0987d86564aee9a9ff15c44caa43c86dac70d7947b9a8d66d2c7ae4268' 
  AND token = 'uXZFgPXS5wE2vkkVJE6nC5D9StGMjQTXA0h8PfdvveE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}