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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6b6be4096593d0f6d62591a1d5ec467cdeadadb5969aa4045c48efc5ab5b249' 
  AND token = 'f8d1w3WUFw7qd9YrUfMJll2dY0UKV9Be4U5UXtppKsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}