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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd460674c08ce870bb8b65d38d5dba1e8900258714dba8e54f5bc1d08fd057a48' 
  AND token = '/pKxZZVSFHA9+vx7YFUwiMc/Dk7v+OGBfzzF55GEUwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}