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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9722f893b188edfd85ad81ffa60991c7ea9e2c4ed0f93ecbb1fe2ad95e92299f' 
  AND token = 'KHN8jyNo/eMX9OHZehnqMFbK5+L5+jHePCPCOhlKz3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}