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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9e8b4c41c2f2790e0efea1e5b2ecce04b39d6b50ab37f5936eee91ad9258e99' 
  AND token = '11okzo8dxnnOKSKQpKpF+uUf7mW6mF7NXxbhb5fXvUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}