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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dfb08d4a84bdab203a8b73b7b174e7e786112ee6f2673f8c19bd6f58aa631c4' 
  AND token = 'QqvMwHZwtrA1wTdeSTiivNJVOPFHgl3FfYOhLdjiyJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}