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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d387a58bf37233f891777bdced10c167dfaa66c53d414bf8ea639f7ed731e23' 
  AND token = 'UUT5B8sv8t/uE159yCItd/m9I3s1JuLegf3Gst95Rgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}