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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd72e1720d88a4599571b8b287a171e2b79bf194dfb169417aa6b1ac04da9df47' 
  AND token = 'GmfGL8BaPRnFs458XNBIFCWeKYaT8Vir84vv/YJY1D4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}