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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c573a439bffb18392bb203dfd68ef8179a58877c8a7ca2e6fa76003f1fddaff' 
  AND token = 'P//MCeast1D4yuYSMFg2U+8GO1n8tVrgeyuZ/crBzJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}