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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e45c4e20356456ce676e512f49073840c80e2d2b5055e15732a93164ed6f4cc5' 
  AND token = 'qu1WrfBUxDuDv+Lndto0LzyTgIlxD/TVKTbjJjI6S8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}