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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cca1f9e602e66eb0004c34015a5ad1430ec849d28db7874028fb1ec606028d10' 
  AND token = 'F6HBo7AFC7mHnYVwsgKV2xmWT3fgjS5qyoAp3HBvUdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}