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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec9039c9f4d10e5c7ff7c2e80a4e2421325f45dd520936a91b82a2c384bd1f12' 
  AND token = 'x74vJ0Io1uDNMIwatH8qDPS8c7sh1VP2ua6gXsEefDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}