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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06e6dce1f7b2e6daa7458ac0101f8e00ad7ff4127dd2a0535d1860a04f884eb1' 
  AND token = '/Jj8EN4t8WmvJhpz6/If0tqtvJkBAfNhLFtO2uBkWV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}