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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfed005719499393a433ef5d412895e248cfd0bc01b21ff05b43ea95191fdfaa' 
  AND token = '7/XkLYhdLUv/r5mMNEE5L9nbrbosECFG227GGvUbp3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}